Role of GPR109A Receptor in the Efficacy of Nicotinic Acid

Nicotinic acid is used to treat dyslipidemia from the past few decades. has capability increase plasma HDL cholesterol concentration, and so it being as a potential pharmacological agent. an unwanted side effect called flushing, which patients compliance this unpleasant . With help of receptor GPR109A for nicotinic possible understand underlying mechanism action effects acid, helped in maximizing reducing flushing effects.GPR109A G protein coupled activated by (NA).The role efficacy discussed paper.